November 2021

 

Nitrous oxide-induced predominantly motor neuropathies: a follow-up study

Young patients, with induced N2O motor neuropathy remain disabled after 5 to 14.5 months of gas withdrawal, despite vitamin B12 supplementation. A longer follow-up is needed to fully appraise the severity of these toxic neuropathies.

Edouard Berling, Guillaume Fargeot, Karine Aure, Tuan Huy Tran, Nathalie Kubis, Pierre Lozeron &
Adrien Zanin Springer (2021) Nitrous oxide-induced predominantly motor neuropathies: a follow-up study

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Nangs, balloons and crackers: Recreational nitrous oxide neurotoxicity

A female university student aged 18 years presented to her general practitioner (GP) with subacute-onset, progressive distal lower limb sensory symptoms and unsteadiness. She had first noticed symptoms three weeks earlier when she awoke with painful tingling and numbness in both feet. Over the following weeks, the sensory symptoms progressed, and she developed bilateral lower limb weakness and impaired balance such that she was unable to dress herself while standing.

Eric BN Evans; Matthew RB Evans  Australian Journal of General Practice (2021) Nangs, balloons and crackers: Recreational nitrous oxide neurotoxicity